Related Experiment Video
Updated: Sep 15, 2025

Assessment of Morphine-induced Hyperalgesia and Analgesic Tolerance in Mice Using Thermal and Mechanical Nociceptive Modalities
Published on: July 29, 2014
Is There a Role for Acute or Chronic Opioid Therapy?
Savannah R Whitfield1, Narayan R Kissoon2
1Department of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
None:
This article underlines the necessity of reasonable opioid use in pain management, advocating for reserved prescriptions for cases where alternative therapies fail. It stresses comprehensive patient evaluation to balance benefits and risks. While opioids offer relief, it is important to utilize nonopioid medications, physical therapy, exercise, and other modalities in addressing pain. This review discusses the evolving landscape of opioid prescribing practices and the associated risks, highlighting the current Centers for Disease Control Guidelines on opioid prescribing. Additionally, it emphasizes the need for continuous evaluation and risk mitigation strategies to promote comprehensive care.
Related Concept Videos
Analgesia and Pain Management
Opioid Analgesics: Synthetic and Semisynthetic Opioids
Opioid Analgesics: Morphine and Other Natural Cogeners
Opioid Receptors: Overview
Drugs Affecting GI Tract Motility: Opioids as Antidiarrheal Agents
Opioids, widely used antidiarrheal agents, mitigate diarrhea by slowing down...
Nociception

