Radiation-induced angiosarcoma of the breast: A rare but aggressive pathology warranting ongoing attention

Radiation-induced angiosarcoma of the breast is a rare and highly aggressive malignant neoplasm. Its incidence is likely to rise in the coming years due to the increasing use of breast-conserving surgery techniques. Changes in the skin colour of the irradiated area in a patient treated with conservative surgery should raise suspicion of this pathology. The diagnostic work-up for this disease includes different imaging modalities including mammography, ultrasound, or magnetic resonance imaging. However, the most accurate diagnostic method is skin biopsy. Treatment typically involves surgical resection, while the role of chemotherapy and radiotherapy is not well established.