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Updated: Sep 15, 2025

Human Skeletal Muscle Biopsy Procedures Using the Modified Bergström Technique

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Published on: September 10, 2014

Muscle involvement in Behçet's syndrome: a case report.

M Ma¹, F Fang², L Zhao³

¹Department of Rheumatology and Immunology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing, PR China; Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, PR China.

International Journal of Oral and Maxillofacial Surgery

|July 17, 2025

Summary

This summary is machine-generated.

Behçet

Keywords:

Behçet’s syndrome Muscle Myositis Tongue Vasculitis

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Area of Science:

Rheumatology and Immunology
Neurology

Background:

Behçet's syndrome is a rare systemic vasculitis.
It typically presents with oral ulcers, genital ulcers, uveitis, and skin lesions.

Observation:

This case highlights a rare presentation of Behçet's syndrome.
The patient exhibited fever, recurrent aphthous ulcers, and myositis affecting the tongue and gastrocnemius muscles.
Biopsies revealed phlebitis in the tongue and muscle fiber degeneration with vasculitis in the gastrocnemius.

Findings:

Myositis, particularly involving the tongue and leg muscles, can be an early or sole manifestation of Behçet's syndrome.
Histopathological findings support vasculitis and muscle inflammation as key features.
Treatment with prednisone and thalidomide effectively reduced symptoms.

Implications:

Clinicians should consider Behçet's syndrome in patients with recurrent oral ulcers and unexplained fever and myositis, even without typical genital or ocular findings.
Early diagnosis and treatment are crucial for managing this rare systemic vasculitis.
This case broadens the understanding of Behçet's syndrome's diverse clinical spectrum.