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Updated: Sep 15, 2025
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Lumped-Parameter and Finite Element Modeling of Heart Failure with Preserved Ejection Fraction
Published on: February 13, 2021
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Demographic disparities in heart failure with preserved ejection fraction
Adhvithi Pingili1, Maneeth Mylavarapu2, Mounika Reddy Vadiyala3
1Department of Internal Medicine, MedStar Union Memorial Hospital, Baltimore, MD, USA.
Heart Failure Reviews
|July 17, 2025
Summary
Demographic factors significantly impact heart failure with preserved ejection fraction (HFpEF). Age, sex, race, and socioeconomic status influence HFpEF prevalence, risk, and outcomes, necessitating tailored approaches.
Area of Science:
- Cardiology
- Public Health
- Health Disparities
Background:
- Heart failure with preserved ejection fraction (HFpEF) is a growing clinical concern.
- Understanding demographic influences is crucial for addressing HFpEF.
- Existing research often lacks comprehensive analysis of diverse populations.
Purpose of the Study:
- To review the multifaceted impact of demographic factors on HFpEF.
- To investigate disparities in HFpEF prevalence, risk, diagnosis, treatment, and outcomes.
- To highlight the need for inclusive research and equitable care.
Main Methods:
- Comprehensive literature review.
- Synthesis of evidence on age, sex, race/ethnicity, and socioeconomic status.
- Analysis of disparities in HFpEF.
Main Results:
- HFpEF incidence increases with age, with age-specific mechanisms.
- Women exhibit a higher predisposition to HFpEF.
- Socioeconomic factors significantly affect access to care and treatment adherence.
Conclusions:
- Demographic factors play a critical role in HFpEF.
- Addressing disparities requires a holistic and inclusive research approach.
- Improving equitable healthcare delivery is essential for better HFpEF patient outcomes.
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