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Acute Kidney Injury Requiring Dialysis Following Percutaneous Coronary Intervention: Insights From the

Deniz Mutlu1, Ozgur Selim Ser1, Dimitrios Strepkos1

  • 1Minneapolis Heart Institute and Minneapolis Heart Institute Foundation, Abbott Northwestern Hospital, Minneapolis, Minnesota, USA.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|July 18, 2025
PubMed

Insights

Acute kidney injury (AKI) requiring dialysis after percutaneous coronary intervention (PCI) affects 0.6% of patients. This complication is linked to high in-hospital and long-term mortality and major adverse cardiovascular events.

Area of Science:

  • Cardiology
  • Nephrology
  • Interventional Cardiology

Background:

  • Acute kidney injury (AKI) requiring dialysis is a severe complication following percutaneous coronary intervention (PCI).
  • This condition presents a significant threat to patient survival and recovery post-PCI.

Purpose of the Study:

  • To evaluate the clinical and procedural factors associated with AKI requiring dialysis after PCI.
  • To determine the outcomes, including mortality and major adverse cardiovascular events (MACE), in patients experiencing AKI post-PCI.

Main Methods:

  • Analysis of a contemporary PCI complication registry (NCT05100940) from 2016-2023.
  • Inclusion of 18,691 patients who underwent PCI, with a focus on the 119 who required dialysis for AKI.
  • Assessment of patient demographics, comorbidities, procedural details, and short-term and long-term outcomes.

Main Results:

  • AKI requiring dialysis occurred in 0.6% of PCI patients.
  • Patients were elderly (mean age 71) with high rates of diabetes (38.7%), CKD (73.9%), heart failure (67.8%), and prior MI (54.0%).
  • In-hospital mortality was 48.7%, with 63.6% experiencing MACE during follow-up, primarily driven by high mortality (62.1%).

Conclusions:

  • AKI necessitating dialysis post-PCI is a rare but critical complication.
  • The study highlights a substantial burden of mortality and MACE in this patient cohort.
  • These findings underscore the need for vigilant monitoring and management strategies for AKI in PCI patients.
Abstract

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