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Actuation of bilayer hydrogels via a cross-stimuli chemical reaction network

Zhongrui Wang1, Yongzheng Xing1, Yuwen Meng1

  • 1National Engineering Research Center for Colloidal Materials, School of Chemistry and Chemical Engineering, Shandong University, Jinan, Shandong 250100, People's Republic of China. Yuwen.meng@sdu.edu.cn.

Chemical Communications (Cambridge, England)
|July 18, 2025
PubMed

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Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
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