Related Experiment Video
Updated: Sep 15, 2025

Ultrasound Assessment of Endothelial-Dependent Flow-Mediated Vasodilation of the Brachial Artery in Clinical Research
Published on: October 22, 2014
Accessory Brachial Artery Causing Delayed Vasospasm After Angiography: A Detailed Analysis of a Case Report
Kazuyuki Mikami1, Yoji Kuramoto2, Takahiro Kuroyama1
1Neurosurgery, Shinko Hospital, Kobe, JPN.
Abstract:
Cerebral angiography remains the gold standard investigation for cerebrovascular disease. Transradial access is increasingly preferred over the transfemoral approach because it facilitates early ambulation and reduces complications at the access site. We report a woman in her 70s who developed delayed peripheral circulatory failure in the digital arteries following transradial cerebral angiography. After inserting a 4-French sheath into the conventional right radial artery, the catheter was advanced toward the subclavian artery but inadvertently entered a small accessory brachial artery with significant resistance, provoking severe vasospasm. The procedure was completed without incident after redirecting the catheter into the main brachial artery. Symptoms gradually appeared 24 hours after the procedure, and after 48 hours, the patient experienced burning pain, weakness, and pallor in her right hand. Angiography via the brachial artery demonstrated diffuse spasm of the radial artery, palmar arch, and digital arteries. Intra-arterial nitroglycerin quickly restored flow and alleviated symptoms. This case illustrates that inadvertent cannulation of an accessory brachial artery during transradial access can lead to delayed digital circulatory failure and that early intra-arterial vasodilator therapy is effective. Careful observation is necessary if such a catheter deviates into a small vessel with an anatomical anomaly, and spasm occurs.
Related Concept Videos
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation
Arteries of the Upper Limbs
Vascular Spasm
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests
Aneurysm II: Clinical Manifestations and Diagnostic Studies
Assessment of blood pressure in brachial artery(one-step method)
Prepare for the Procedure:

