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Related Experiment Video

Updated: Sep 14, 2025

Experimental Viral Infection in Adult Mosquitoes by Oral Feeding and Microinjection
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Mosquito-Borne Infections in International Travelers.

Robert J Rolfe1,2, Sofia Zavala1,2, Elizabeth R Blackwood3

  • 1Department of Medicine, Duke University School of Medicine, Durham, NC, USA.

Wilderness & Environmental Medicine
|July 21, 2025
PubMed
Summary

Returning travelers frequently contract mosquito-borne illnesses like arboviruses and malaria. Prevention involves insect protection and, for malaria, chemoprophylaxis, while some arboviruses offer vaccine prevention.

Keywords:
chikungunyadengue fevermalariamosquito-borne diseasetravelyellow fever

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Area of Science:

  • Medical Entomology
  • Travel Medicine
  • Infectious Diseases

Background:

  • Mosquito-borne infections pose a significant health risk to international travelers.
  • Healthcare providers must consider these infections in evaluating ill returning travelers.

Purpose of the Study:

  • To provide an overview of common mosquito-borne infections in travelers.
  • To highlight recent updates in the diagnosis and prevention of these diseases.

Main Methods:

  • A narrative review of the medical literature published within the last 5 years.
  • Consultation of resources from the US Centers for Disease Control and Prevention (CDC) and the US Food and Drug Administration (FDA).

Main Results:

  • Arboviral infections and malaria are the most common mosquito-borne illnesses diagnosed in returning travelers.
  • Vaccine-preventable arboviral infections include chikungunya, yellow fever, and Japanese encephalitis.
  • Dengue fever lacks a US-approved vaccine, and Zika virus infections have recently decreased.

Conclusions:

  • Mosquito-borne illness risk is mitigated through behavioral changes and protective measures like repellents and netting.
  • Malaria prevention includes appropriate chemoprophylaxis.
  • Awareness and preventive strategies are crucial for travelers' health.