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Recurrent prostatic stromal sarcoma (PSS): A case report and literature review
Mohammad Reza Nowroozi1, Mohammad Hamidi Madani1, Amirreza Farzin1
1Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Urology Case Reports
|July 21, 2025
Summary
Prostatic stromal sarcoma (PSS) is a rare prostate cancer. This case highlights successful surgical management and organ preservation for recurrent high-grade PSS, emphasizing tailored treatment and follow-up.
Area of Science:
- Oncology
- Surgical Pathology
- Urologic Oncology
Background:
- Prostatic stromal sarcoma (PSS) is an exceedingly rare mesenchymal neoplasm originating in the prostate gland.
- Accurate diagnosis and effective management of PSS remain challenging due to its rarity and aggressive nature.
Observation:
- A case of high-grade recurrent prostatic stromal sarcoma in a 49-year-old male patient is presented.
- The patient underwent complete surgical excision, achieving successful organ preservation.
Findings:
- The literature review covers diagnostic difficulties, key histopathological characteristics, and advancements in surgical techniques for PSS.
- Robotic-assisted surgery is emerging as a viable approach for PSS management.
Implications:
- Individualized treatment strategies are crucial for optimizing outcomes in patients with aggressive prostatic stromal sarcoma.
- Long-term follow-up is essential for monitoring recurrence and ensuring sustained patient well-being after PSS treatment.
