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Updated: Sep 14, 2025

Harnessing the Bioorthogonal Inverse Electron Demand Diels-Alder Cycloaddition for Pretargeted PET Imaging
Published on: February 3, 2015
CD45-targeted PET enables the visualization of inflammatory conditions
Chongjiao Li1, Zhendong Song1, Qilong Hu1
1Department of Radiology and Imaging Sciences, Emory University Atlanta, Georgia 30322, USA.
None:
Inflammation is a major contributor to human mortality, accounting for over 50% of deaths worldwide. Therefore, there is an urgent need for early and accurate diagnostic methods. PET imaging targeting leukocyte common antigen CD45 presents a promising approach for detecting inflammation and monitoring therapeutic responses.
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