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Image Findings of Breast Cancer-Related Elastosis: A Case Report
Yu Takano1, Shoji Oura2, Mariko Honda2
1Department of Surgery, Kishiwada Tokushukai Hospital, Kishiwada, Japan.
Case Reports in Oncology
|July 21, 2025
Summary
Elastosis in breast cancer is better visualized on cranio-caudal mammography (CC MMG) than MLO MMG. This imaging characteristic, along with specific ultrasound and MRI findings, aids in diagnosis.
Area of Science:
- Radiology
- Oncology
- Pathology
Background:
- Elastosis, a fibrous component in breast tissue, has been understudied in breast cancer imaging.
- Accurate imaging is crucial for early breast cancer detection and diagnosis.
Observation:
- A 70-year-old woman presented with a palpable breast tumor.
- Mammography (MMG) revealed an irregular mass with pleomorphic calcifications, better seen on cranio-caudal (CC) views than medio-lateral-oblique (MLO) views.
- Ultrasound showed a lobulated mass with specific echo characteristics. MRI demonstrated low T1 and T2 signal intensities with rim enhancement.
Findings:
- Pathology confirmed invasive breast cancer with significant elastosis.
- The tumor exhibited specific imaging features including calcifications, echogenicity, and MRI signal characteristics.
- Elastosis areas were encompassed by malignant cells.
Implications:
- Radiologists should recognize that breast cancer-related elastosis is more clearly depicted on CC MMG.
- Enhanced posterior echoes on ultrasound and specific MRI signal intensities (low T1, absent T2) are potential indicators.
- These imaging findings can assist physicians in diagnosing breast cancer with elastosis.
