Related Experiment Video
Updated: Sep 14, 2025

Author Spotlight: Advancing Facial Rejuvenation Therapy with Post-Laser Salicylic Acid Application
Published on: September 27, 2024
Evidence-Based Topical Therapy for Facial Scars in Diverse Skin Types
Sarah Kazemeini1, Ahmed Nadeem-Tariq2, Anahat Luthra3
1Medical Education, Kirk Kerkorian School of Medicine, University of Nevada, Las Vegas, Las Vegas, USA.
Abstract:
Facial trauma repair frequently results in scarring that can significantly impact psychological well-being, particularly in highly visible areas, such as the face. While topical agents provide a non-invasive means of optimizing scar outcomes, clinical guidance regarding their use remains limited, especially for diverse skin types. This narrative review synthesizes findings from PubMed, Google Scholar, and Embase, prioritizing randomized controlled trials, meta-analyses, and expert consensus. Evidence supports the use of silicone gel, corticosteroids, retinoids, vitamin C, niacinamide, and onion extract for scar modulation. A timeline-based model was developed to guide agent selection across healing phases, emphasizing early intervention after re-epithelialization and tailored regimens for patients with Fitzpatrick skin types IV-VI. This review proposes a phase-specific approach to facial scar optimization that integrates skin phototype considerations. Further research is needed to validate the safety and efficacy of combinatory topical regimens across diverse populations.
Related Concept Videos
Clinical Applications of Epidermal Stem Cells
Skin Cancer
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Renewal of Skin Epidermal Stem Cells
Skin Diseases and Disorders
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

