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Evaluating Monaco 6.2.2 in complex radiotherapy across matched LINACs: improved MLC modelling and dose accuracy with
Luis Muñoz1,2, Peter McLoone3, Peter Metcalfe4
1Genesiscare Flinders Private Hospital, Bedford Park, SA, Australia. luis.munoz@genesiscare.com.
Physical and Engineering Sciences in Medicine
|July 21, 2025
Summary
The updated Monaco TPS virtual source model (VSM) 2.0 improves multileaf collimator (MLC) modeling for stereotactic radiotherapy (SRT). This advancement enhances dosimetric performance and simplifies workflows for precise SRT and SABR delivery.
Area of Science:
- Medical Physics
- Radiation Oncology
- Computational Dosimetry
Background:
- The Monaco Treatment Planning System (TPS) utilizes virtual source models (VSMs) for accurate dose calculation.
- Previous VSM versions required extensive characterization of multileaf collimator (MLC) and jaw parameters.
- Stereotactic radiotherapy (SRT) demands high precision in dose delivery, necessitating accurate beam modeling.
Purpose of the Study:
- To evaluate the updated Monaco TPS VSM 2.0, which simplifies beam modeling by removing editable MLC and jaw parameters.
- To assess the impact of VSM 2.0 on dosimetric accuracy for stereotactic radiosurgery (SRS) and stereotactic body radiation therapy (SBRT) cases.
- To compare VSM 2.0 performance against a validated custom VSM 1.6 and Elekta's Accelerated Go Live 6 MV FFF beam model.
Main Methods:
- VSM 2.0 was implemented and evaluated on two beam-matched linear accelerators (LINACs).
- MLC characteristics were measured using a high-resolution detector.
- Output factors (OPF), ion chamber measurements in a thorax phantom, and recalculations of clinical SRT cases were performed.
- Gamma analysis was used to compare dose distributions between VSM 2.0 and previous models.
Main Results:
- VSM 2.0 demonstrated improved MLC modeling capabilities.
- Ion chamber measurements met IAEA TD1583 tolerances.
- Gamma pass rates (1%, 1 mm) showed improvement for SRS and SBRT treatments on matched LINACs.
- VSM 2.0 offers enhanced agility in MLC modeling and simplifies commissioning workflows.
Conclusions:
- VSM 2.0 represents a significant advancement in Monte Carlo-based TPS beam modeling.
- The updated model provides improved dosimetric accuracy and operational simplicity for SRT and SBRT.
- VSM 2.0 facilitates more consistent and high-quality beam models, enhancing treatment delivery precision.

