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Updated: Sep 14, 2025

Preparation of N-2-alkoxyvinylsulfonamides from N-tosyl-1,2,3-triazoles and Subsequent Conversion to Substituted Phthalans and Phenethylamines
Published on: January 3, 2018
Ruthenium(II)-Catalyzed Annulation of Vinyl Sulfoxonium Ylides with Arynes for the Rapid Synthesis of Functionalized
Shashank Shrotriya1, Fathima Dinsha Paravakkal1, Akkattu T Biju1
1Department of Organic Chemistry, Indian Institute of Science, Bangalore-560012, India.
Abstract:
A mild and general strategy is demonstrated for the Ru(II)-catalyzed annulation of vinyl sulfoxonium ylides with arynes, resulting in the formation of 1-naphthols. The initially generated vinyl Ru-carbenoid underwent cyclization to form a disubstituted furan, which was intercepted by the aryne released from the TMS-triflate to form the 1-naphthol, thereby suppressing the direct arylation of the ylide. The method features broad applicability, good functional group tolerance, and potential for diversification, making it a valuable tool for accessing various arylated 1-naphthols.
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