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Updated: Sep 14, 2025

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
Acute code stroke activations seen in the emergency department: how often are we missing the mark?
Emily Li1, Mohitt Khinda2, Aikta Verma3,4
1Sunnybrook Health Sciences Centre, Sunnybrook Research Institute, Toronto, ON, Canada.
One in three code stroke activations did not meet criteria, leading to inefficient resource use. Improving adherence to stroke protocols can reduce non-compliant activations and conserve healthcare resources.
Area of Science:
- Neurology
- Emergency Medicine
- Healthcare Management
Background:
- Code stroke activations mobilize critical healthcare resources.
- Evaluating compliance with code stroke criteria is essential for resource optimization.
- Previous studies have not fully assessed non-compliant activations and their impact on acute stroke care.
Purpose of the Study:
- To determine the proportion of non-compliant code stroke activations.
- To analyze acute treatments and healthcare utilization following non-compliant activations.
- To identify factors contributing to non-compliant code stroke activations.
Main Methods:
- A multicentre health records review was conducted.
- Adult patients experiencing code stroke activations in emergency departments (ED) were analyzed.
- Non-compliant activations were defined as those not meeting institutional criteria.
Main Results:
- 30.5% of 1028 code stroke activations were non-compliant.
- Incorrect last seen normal time determination was the primary cause of non-compliance.
- Non-compliant activations were less likely to receive reperfusion therapy or stroke unit admission.
Conclusions:
- A significant proportion of code stroke activations are non-compliant with established criteria.
- Simplifying protocols and utilizing simulation exercises can improve adherence.
- Reducing non-compliant activations can conserve vital healthcare resources and improve patient care pathways.
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