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Updated: Sep 14, 2025

Operant Sensation Seeking in the Mouse
Published on: November 10, 2010
Recreational Use of Nitrous Oxide (N2O) and Sensation-Seeking Among Adolescents in Sweden: A Cross-Sectional Study
Håkan Källmen1, Matz Larsson2,3
1Department of Psychology, Uppsala University, Uppsala, Sweden.
Background:
Inhalation (Sniffing) of N2O among adolescents has increased in Sweden during recent years. Both neurological and thromboembolic consequences have been reported. This study aims to evaluate the association between a sensation-seeking personality and sniffing of N2O among students attending schools in Stockholm.
Method:
Students, 15-18 years old, from 77% of schools in Stockholm participated summing up to 8389 boys and 8425 girls. Data was self-reported. Both crude and adjusted regression models were calculated.
Results:
In the crude model, sensation seeking was associated with higher odds for use of N2O OR = 4.22 (confidence interval = 3.66-4.86). When controlling for binge drinking of alcohol, use of nicotine and cannabis, parental education, own spending money per month, and school-related covariates and also considering gender, sensation-seeking was still related to higher odds OR = 1.50 (CI = 1.11-2.01).
Conclusions:
The results suggest that sensation seeking is associated with sniffing of N2O in boys as well as girls.
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