Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Modified-Release Drug Delivery Systems: Rate-Programmed I

Modified-Release Drug Delivery Systems: Rate-Programmed I

Rate-programmed drug delivery systems (DDS) are designed to release drugs at specific, controlled rates to maintain consistent therapeutic levels. These systems are categorized based on their release mechanisms, including dissolution-controlled DDS, diffusion-controlled DDS, and combined dissolution-diffusion-controlled DDS.In dissolution-controlled DDS, the release rate depends on the slow dissolution of the drug itself or the surrounding matrix. Drugs with inherently slow dissolution rates,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Psychological Impact and Workload of COVID-19 on Healthcare Workers in China During the Early Time of the Pandemic: A Cross-sectional Study.

Disaster medicine and public health preparedness·2022

Same author

Manipulation of Band Alignment in Two-Dimensional Vertical WSe<sub>2</sub>/BA<sub>2</sub>PbI<sub>4</sub> Ruddlesden-Popper Perovskite Heterojunctions via Defect Engineering.

The journal of physical chemistry letters·2022

Same author

Efficient and Stable Perovskite Solar Cells via CsPF<sub>6</sub> Passivation of Perovskite Film Defects.

The journal of physical chemistry letters·2022

Same author

Development of an Indirect ELISA Kit for Rapid Detection of Varicella-Zoster Virus Antibody by Glycoprotein E.

Frontiers in microbiology·2022

Same author

Adhesive Materials Inspired by Barnacle Underwater Adhesion: Biological Principles and Biomimetic Designs.

Frontiers in bioengineering and biotechnology·2022

Same author

Protective effect of cinnamaldehyde on channel catfish infected by drug-resistant Aeromonas hydrophila.

Microbial pathogenesis·2022

Search research articles

Related Experiment Video

Updated: May 8, 2026

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials

Published on: January 10, 2025

Engineering next-generation smart delivery materials for dentistry.

Sumanta Ghosh¹, Chao Liang¹, Sang Jin Lee¹

¹Applied Oral Sciences and Community Dental Care, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China.

Advances in Colloid and Interface Science

|July 22, 2025

Summary

Smart dental biomaterials offer precise drug delivery by responding to stimuli like pH and temperature. These advanced materials improve treatment efficacy and reduce side effects for various dental conditions.

Keywords:

Dentistry Drug delivery Infection control Smart biomaterials Stimuli-responsive

More Related Videos

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material

Published on: December 20, 2024

Impact of Fabrication Techniques and Polishing Procedures on Surface Roughness of Denture Base Resins

Impact of Fabrication Techniques and Polishing Procedures on Surface Roughness of Denture Base Resins

Published on: January 17, 2025

Related Experiment Videos

Last Updated: May 8, 2026

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials

Roughness Impact of Piezoelectric Dental Scaler on Two Distinct Flowable Composite Filling Materials

Published on: January 10, 2025

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material

Published on: December 20, 2024

Impact of Fabrication Techniques and Polishing Procedures on Surface Roughness of Denture Base Resins

Impact of Fabrication Techniques and Polishing Procedures on Surface Roughness of Denture Base Resins

Published on: January 17, 2025

Area of Science:

Biomaterials Science
Dental Therapeutics
Drug Delivery Systems

Background:

Stimuli-responsive biomaterials have advanced significantly over the last 20 years.
Smart dental biomaterials enable precise, on-demand delivery of therapeutic agents.
These materials leverage specific stimuli to enhance drug efficacy and minimize side effects.

Purpose of the Study:

To review smart biomaterial platforms for dental and soft tissue applications.
To summarize stimuli-responsive drug delivery systems based on pH, enzyme, temperature, light, ultrasound, electricity, and pressure.
To discuss emerging smart platforms in clinical trials for dental conditions.

Main Methods:

Systematic examination of smart biomaterial platforms for dental applications.
Comprehensive summarization of delivery systems categorized by stimuli type.
Review of newly developed platforms and clinical trial progress.

Main Results:

Diverse stimuli-responsive biomaterials are being developed for targeted dental therapies.
Platforms responding to pH, enzymes, temperature, light, ultrasound, electricity, and pressure are detailed.
Several novel smart platforms are under investigation for clinical use in dentistry.

Conclusions:

Smart drug delivery systems represent the state-of-the-art in modern dentistry.
These advanced platforms offer significant potential for infection control, inflammation management, tissue regeneration, and immunotherapy.
Further development of next-generation smart biomaterials is crucial for addressing unmet clinical needs.