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Updated: Sep 14, 2025

Author Spotlight: Scaling Microalgal Biotechnology for Enhanced Biomethane Production
Published on: March 22, 2024
Unlocking the algae toolbox: Cutting-edge tools for environmental and biotechnological solutions
Vu Khac Hoang Bui1, Le Gia Trung2, Ha Huu Do3
1Laboratory for Advanced Nanomaterials and Sustainable Energy Technologies, Institute for Computational Science and Artificial Intelligence, Van Lang University, Ho Chi Minh City, Viet Nam; Faculty of Applied Technology, School of Technology, Van Lang University, Ho Chi Minh City, Viet Nam.
Advancements in the algae toolbox, including genetic engineering and AI, enhance biotechnology and sustainability. Future research focuses on AI and synthetic biology for optimized algal cultivation and bioproducts.
Area of Science:
- Biotechnology and Environmental Science
- Focuses on the application of algae in various industrial and environmental sectors.
Background:
- Algae are versatile photosynthetic organisms with increasing importance in biotechnology and sustainable industries.
- Recent progress has significantly expanded the available tools for algal research and application.
Purpose of the Study:
- To critically review the latest advancements in algal research and technology.
- To highlight the role of new tools in industrial scale-up and sustainability.
Main Methods:
- Examination of cutting-edge technologies such as CRISPR-Cas9 gene editing, high-throughput omics, and machine learning.
- Integration of remote sensing, optical sensors, flow cytometry, biosensors, and environmental DNA for monitoring.
- Analysis of innovations supporting industrial scale-up in biofuels, pharmaceuticals, aquaculture, and bioremediation.
Main Results:
- Significant improvements in screening, monitoring, characterization, and large-scale production technologies for algae.
- Enhanced precision in tracking algal dynamics through advanced sensing and omics approaches.
- Progress in boosting productivity and sustainability for various algal-based industries.
Conclusions:
- Despite advancements, challenges remain in the economic viability and environmental sustainability of large-scale algal production.
- Future research should integrate artificial intelligence, IoT-enabled sensing, and synthetic biology for optimized cultivation and harvesting.
- The review underscores the transformative potential of emerging tools in advancing algal biotechnology and global sustainability.
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