Etiology of congenital glaucoma. Genetic and extragenetic factors

Congenital glaucoma (simple, associated and secondary) has been studied for the frequency of mesodermal anomalies and malformations (skeletal changes, congenital heart diseases, neurological alterations). But congenital glaucoma is not due solely to genetic factors: it is more likely that most cases result from interaction between genetic predisposition and a combination of environmental causes.