Related Experiment Video
Updated: Sep 14, 2025
12:03
Myocardial Infarction and Functional Outcome Assessment in Pigs
Published on: April 25, 2014
28.1K
COVID-19 with acute myocardial infarction evaluated using multimodal imaging: A case report
Jingyao Wang1, Yachao Li1, Mengjie Lei1
1Department of Cardiology, Langfang People's Hospital, Hebei Medical University, Langfang Core Laboratory of Precision Treatment of CAD, Langfang, China.
Medicine
|July 23, 2025
Summary
Coronavirus disease 2019 (COVID-19) may trigger acute myocardial infarction by causing inflammation and hypercoagulability, destabilizing coronary plaques. Monitoring inflammatory markers is crucial for patients with COVID-19 and cardiovascular risks.
Area of Science:
- Cardiology
- Infectious Diseases
- Vascular Biology
Background:
- Cardiovascular complications, including acute myocardial infarction, persist as a concern despite the diminished global impact of coronavirus disease 2019 (COVID-19).
- COVID-19 may destabilize pre-existing coronary plaques via systemic inflammation and hypercoagulability.
Purpose of the Study:
- To investigate the potential role of COVID-19 in acute myocardial infarction development.
- To offer insights into diagnostic and therapeutic strategies for patients experiencing cardiovascular events post-COVID-19.
Main Methods:
- A case study of a 41-year-old woman with no prior cardiovascular risk factors presenting with chest pain 5 days after COVID-19 diagnosis.
- Diagnostic procedures included electrocardiography, troponin I measurement, emergency coronary angiography, and optical coherence tomography.
- Interventions involved thrombus aspiration, optical coherence tomography-guided angioplasty, and initiation of lipid-lowering and dual antiplatelet therapies.
Main Results:
- Coronary angiography revealed acute anterior myocardial infarction due to 90% stenosis and thrombus in the left anterior descending artery.
- Optical coherence tomography identified vulnerable, non-ruptured plaques with macrophages and cholesterol crystals.
- Post-procedural imaging indicated residual plaque burden and myocardial injury, suggesting dual ischemic and inflammatory processes.
Conclusions:
- COVID-19 may induce acute myocardial infarction by promoting atherosclerotic plaque destabilization through inflammation and hypercoagulability.
- Monitoring inflammatory markers and considering anti-inflammatory treatments are essential for managing such patients.
More Related Videos
Related Concept Videos
01:30Acute Coronary Syndrome III: Diagnostic Studies
23
Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
23
01:30Acute Coronary Syndrome I: Introduction
80
Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...
80
01:19Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
47
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
47
01:28Imaging Studies for Cardiovascular System V: CT
66
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
66
01:27Myocarditis II: Clinical Features and Diagnostic Tests
24
Myocarditis is an inflammation of the heart muscle. The symptoms vary widely, encompassing asymptomatic presentations to severe, acute manifestations.Clinical PresentationAsymptomatic cases: In some instances, myocarditis may be asymptomatic, with the infection resolving without intervention. These cases often go undetected unless discovered incidentally through diagnostic imaging or tests conducted for other reasons.General Early Symptoms: Early symptoms of myocarditis are non-specific and can...
24
01:28Acute Coronary Syndrome IV: Interprofessional Care
30
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
30