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Updated: Sep 14, 2025

Synthesis of Hypervalent Iodonium Alkynyl Triflates for the Application of Generating Cyanocarbenes
Published on: September 8, 2013
Sulfoxonium ylides as carbon radical precursors in three-component carbohalogenation of alkenes
Ning Xian1, Jiang Yin1, Xiaochen Ji1
1College of Chemistry, Xiangtan University, Xiangtan 411105, China. hwhuang@xtu.edu.cn.
Abstract:
Herein, we developed a novel visible-light-induced photoredox platform for general three-component difunctionalization of alkenes with aqueous sulfoxonium ylides as carbon radical precursors. This reaction utilizes various alkenes as substrates and employs cost-effective, non-toxic metal salts as halogen donors. The process proceeds under mild aqueous conditions without requiring acid or base additives, offering a simple and environmentally benign strategy for the synthesis of structurally diverse C(sp3)-rich organic halides with excellent chemo- and regioselectivity profiles.
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