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![[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F59739.jpg&w=3840&q=50)
[(DPEPhos)(bcp)Cu]PF6: A General and Broadly Applicable Copper-Based Photoredox Catalyst
Published on: May 21, 2019
Copper-catalyzed selective 1,2-disulfidation of 1,3-dienes
Shuilin Liu1, Pu Chen1, Ning Liu1
1College of Chemistry and Environmental Engineering, Hunan Institute of Technology, Hengyang, Hunan, 421200, China. 13873019351@163.com.
Abstract:
A copper-catalyzed protocol for the regioselective 1,2-bis-sulfuration of 1,3-dienes has been developed. This transformation utilizes sulfonyl chlorides and thiols as bifunctional sulfur sources, proceeding under mild conditions to afford valuable bis-sulfurated frameworks. Mechanistic investigations suggest a radical-mediated process, highlighting that the conjugated diene moiety is essential for the efficacy of this protocol. This method provides a versatile and efficient approach for the installation of diverse sulfur functionalities onto conjugated diene skeletons in a single synthetic operation.
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