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Related Experiment Video

Updated: Sep 14, 2025

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

Generation and Characterization of Right Ventricular Myocardial Infarction Induced by Permanent Ligation of the Right Coronary Artery in Mice

Published on: February 1, 2022

Isolated right ventricular infarction - Unmasking the masquerader.

Srista Manandhar¹, Sunit Chhetri¹, Jordan Tannenbaum¹

¹Department of Cardiovascular Medicine, Atrium Health Wake Forest Baptist, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

Journal of Cardiology Cases

|July 23, 2025

Summary

Isolated right ventricular (RV) infarction is rare and hard to diagnose. Cardiac MRI is crucial for identifying this condition and indicates a good prognosis for patients with RV dysfunction.

Keywords:

Cardiac magnetic resonance Myocardial infarction Right ventricle

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Area of Science:

Cardiology
Diagnostic Imaging

Background:

Right ventricular (RV) infarction often accompanies left ventricular (LV) myocardial infarction.
Isolated RV infarction is uncommon and presents diagnostic challenges.

Observation:

A 65-year-old man presented with non-ST elevation myocardial infarction.
Coronary angiogram revealed no obstructive coronary artery disease.
Cardiac MRI showed late gadolinium enhancement (LGE) in the RV free wall only, aiding diagnosis.

Findings:

Cardiac MRI confirmed isolated RV infarction.
The patient's RV dysfunction normalized on follow-up echocardiogram.
Late gadolinium enhancement (LGE) is a key imaging biomarker for RV infarction.

Implications:

Cardiac MRI is vital for diagnosing isolated RV infarction, especially when clinical presentation is ambiguous.
Early diagnosis and therapy can lead to RV functional recovery.
Isolated RV infarction may have a favorable prognosis with appropriate management.