Related Experiment Video
Updated: Sep 14, 2025

Failure of Cleaning Verification in Pharmaceutical Industry Due to Uncleanliness of Stainless Steel Surface
Published on: August 11, 2017
Streamlining one-dose package-handling process improves operational efficiency when dispensing drugs: A retrospective
Takahiro Kato1,2, Miki Kato1, Kazuyo Nagashiba1
1Department of Pharmacy, Aichi Medical University Hospital, 1-1 Yazakokarimata, Nagakute city, Aichi 480-1195, Japan.
Optimizing one-dose package (ODP) verification workflows significantly reduced hospital pharmacy dispensing times. This strategy improved efficiency without increasing pharmacist workload, demonstrating the impact of streamlined processes.
Area of Science:
- Pharmacy Practice
- Health Services Research
- Drug Dispensing Efficiency
Background:
- Japanese pharmacists seek to enhance efficiency and communication through process simplification and protocol development.
- While automated dispensing systems show promise, empirical data on their impact on pharmacy efficiency remains limited.
- This study investigates key factors influencing pharmacist efficiency in drug dispensing operations.
Purpose of the Study:
- To identify factors affecting pharmacist dispensing time in a hospital setting.
- To evaluate the impact of implementing workflow optimization strategies on dispensing efficiency.
- To determine if efficiency gains can be achieved without altering staffing levels.
Main Methods:
- Retrospective analysis of daily hospital pharmacy reports from two consecutive years (2020-2022).
- Primary outcome measure was the mean duration of drug dispensing.
- Multiple regression analyses were employed to identify significant factors influencing dispensing time, followed by intervention and outcome evaluation.
Main Results:
- The prescription/pharmacist ratio, number of one-dose package (ODP) prescriptions, and handling of powdered drugs were significant factors affecting dispensing time.
- Implementation of an optimized ODP verification workflow led to a significant decrease in mean dispensing time (20.0 ± 4.0 min to 18.5 ± 3.6 min).
- The proportion of tasks completed within 20 minutes increased from 56.3% to 73.6% post-intervention, indicating enhanced efficiency.
Conclusions:
- Streamlining the one-dose package (ODP) verification process is a key strategy for improving hospital pharmacy dispensing efficiency.
- Workflow optimization can reduce dispensing times and increase task completion rates without necessitating changes in staffing.
- Further multicenter research is recommended to validate these findings across different healthcare settings.
Related Concept Videos
Dosage Regimen: Fixed Dose
Fixed-dose regimens can be used for various routes of administration, including intravenous (IV) injections and oral medications. For IV administration, a predetermined amount of the drug is...
Drug Distribution as One-Compartment Model and Elimination by Nonlinear Pharmacokinetics: Overview
For instance, consider the metabolism of sodium salicylate. This compound is metabolized into two distinct substances: a glucuronide and a glycine conjugate. The rate of conjugation depends...
One-Compartment Open Model for IV Bolus Administration: Estimation of Elimination Rate Constant, Half-Life and Volume of Distribution
Drug Delivery: Miscellaneous Routes
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
One-Compartment Open Model for IV Bolus Administration: General Considerations
The drug's presence in the body is defined by an equation representing the difference between the rates of drug entry and exit. Key parameters—elimination rate constant,...
Biopharmaceutics and Pharmacokinetics: Overview

