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Updated: Sep 14, 2025

Implantation and Monitoring by PET/CT of an Orthotopic Model of Human Pleural Mesothelioma in Athymic Mice
Published on: December 21, 2019
Paraneoplastic Hypoglycaemia in a Patient With Solitary Fibrous Tumor of Pleura
Asmita A Mehta1, Valiyaparambil Pavithran Praveen2, Valathara Pradeep Lakshmi Priya1
1Department of Respiratory Medicine Amrita Institute of Medical Sciences and Research Kochi India.
Abstract:
Solitary fibrous tumours (SFTs) are rare spindle cell neoplasms, predominantly benign, comprising less than 2% of all soft tissue masses. In rare cases, SFTs can lead to Doege-Potter syndrome, a paraneoplastic condition characterised by hypoglycaemia due to elevated levels of insulin-like growth factor II (IGF-II). Patients typically present with symptomatic hypoglycaemia related to this hormonal dysregulation. We report the case of a 70-year-old man who presented with weight loss, cough, fatigue, tingling, and episodes of confusion associated with recurrent hypoglycaemia. Chest radiography revealed a large soft tissue mass in the right lower hemithorax, and CT-guided biopsy confirmed tumour infiltration in the basal segment of the right lower lobe.
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