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Updated: Sep 14, 2025

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Home-Based Prescribed Pulmonary Exercise in Patients with Stable Chronic Obstructive Pulmonary Disease

Published on: August 24, 2019

Pulmonary Function Among COVID-19 Patients in Home Isolation Program.

Narongkorn Saiphoklang^1,2,3, Pitchayapa Ruchiwit¹, Apichart Kanitsap¹

¹Department of Internal Medicine, Faculty of Medicine, Thammasat University, Pathum Thani 12120, Thailand.

Medical Sciences (Basel, Switzerland)

|July 23, 2025

Summary

Mild COVID-19 can cause lasting lung function issues, even in patients managed at home. Nearly a third of participants showed abnormal pulmonary function, primarily restrictive patterns and small airway disease, highlighting the need for long-term monitoring.

Keywords:

COVID-19 home isolation program pulmonary function restrictive lung pattern small airway disease

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Area of Science:

Pulmonology
Infectious Diseases
Public Health

Background:

Mild coronavirus disease 2019 (COVID-19) patients are typically treated as outpatients.
Pulmonary function in this demographic remains under-explored.
This study investigates lung function abnormalities in COVID-19 patients undergoing home isolation.

Purpose of the Study:

To determine the prevalence and types of abnormal lung functions in patients with mild COVID-19 managed under home isolation.
To assess pulmonary function changes at baseline and after 3-month follow-up.

Main Methods:

A prospective study involving 250 asymptomatic or mild COVID-19 patients with normal chest radiographs.
Spirometry measurements including FEV1, FVC, PEF, FEF25-75, and BDR were collected at baseline and 3-month follow-up.
Abnormal lung functions were categorized into specific patterns like airway obstruction and restrictive defects.

Main Results:

28.4% of patients exhibited abnormal lung functions, predominantly restrictive patterns (14.4%) and small airway disease (8.4%).
Significant changes from baseline were observed in FVC, FEV1/FVC ratio, PEF, and FEF25-75.
Higher body mass index correlated with a reduced risk of abnormal lung function.

Conclusions:

A significant proportion of mild COVID-19 outpatients experience residual pulmonary impairment.
Restrictive patterns and small airway disease are the most common ventilatory defects observed.
Further long-term studies are warranted to understand the full impact of mild COVID-19 on lung health.