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In-body current path manipulation with minimal attenuation
Donghyeon Kang1,2, Byung-Joon Park1,2, Joon-Ha Hwang2,3
1Department of Materials Science and Engineering, Yonsei University, Seoul 03722, Republic of Korea.
This study introduces a new method for wireless power transfer neuromodulation using an in-body focusing electrode. This technique enhances therapeutic efficacy by concentrating currents for targeted neural system modulation.
Area of Science:
- Biomedical Engineering
- Neuroscience
- Wearable Technology
Background:
- Wireless power transfer (WPT) offers a battery-free alternative for neuromodulation implants.
- Current WPT methods face challenges including low efficiency, shallow penetration, and safety concerns, limiting therapeutic efficacy.
Purpose of the Study:
- To develop an advanced targeted neuromodulation technology by manipulating and concentrating in-body currents.
- To overcome the limitations of conventional WPT-based neuromodulation.
Main Methods:
- Utilized triboelectric current generated by human movement, characterized by low frequency and high impedance.
- Implanted a focusing electrode to direct and concentrate the triboelectric current towards the target neural area.
- Evaluated current attenuation irrespective of electrode size, implantation site, and depth.
Main Results:
- Demonstrated successful concentration of triboelectric current with minimal attenuation.
- Confirmed therapeutic efficacy in modulating damaged neural systems.
- Validated the safety of the developed neuromodulation technology.
Conclusions:
- The developed in-body current focusing technique significantly enhances targeted neuromodulation.
- This technology shows potential for next-generation neuromodulation therapies, improving efficacy and safety.
- Overcomes key limitations of existing wireless power transfer neuromodulation systems.
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