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Ophthalmic Quality of Life and Its Association With Visual Function, Accommodative and Binocular Vision Performance
Fatemeh Rafiei1, Khosrow Jadidi2, Farhad Nejat3
1Rehabilitation Research Center, Department of Optometry, School of Rehabilitation Sciences, Iran University of Medical Sciences, Tehran, Iran.
Purpose:
To investigate the relationship between ophthalmic quality of life with visual function and accommodative/binocular vision performance in patients with keratoconus (KCN), using the Keratoconus Outcomes Research Questionnaire (KORQ).
Methods:
Seventy patients with KCN were recruited in this study (average age: 27.04 ± 5.60). A Persian adaptation of the KORQ was developed, and its psychometric properties were evaluated through Rasch analysis. The associations between study variables and the KORQ subscales, activity limitations (AL-S) and symptoms (S-S), were evaluated through linear regression models.
Results:
The Persian KORQ demonstrated good psychometric properties after removing items 5 and 8 from the AL-S and items 4 and 5 from the S-S. The analysis showed a statistically significant direct association between the AL-S score and age (β: 0.280, P < 0.05). In addition, there was a statistically significant direct relationship between the AL-S score with best-corrected visual acuity in the better eye (β: 0.279, P = 0.048), binocular contrast sensitivity (β: 0.319, P = 0.033), and steep keratometry in the better eye (β: 0.409, p-0.007). The near negative fusional vergence parameters-blur (β: -0.460, P = 0.012), break (β: -0.403, P = 0.027), and recovery (β: -0.391, P = 0.033)-showed a statistically significant inverse association with the S-S score.
Conclusions:
The Persian KORQ is a reliable tool for assessing ophthalmic quality of life in Persian-speaking patients with KCN. The KCN-related AL-S are primarily influenced by age, basic visual functions, and the severity of KCN in the better eye. Deficits in certain binocular vision metrics, particularly a diminished near negative fusional vergence amplitude, may contribute to the symptoms reported by patients with KCN.
