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Updated: Sep 14, 2025

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
[THERAPY IN PATIENTS AFFECTED BY BREAST AND PROSTATE CANCER]
Adi David1, Sharon Eilon2, Shaked Lev-Ari3
1Tal Center for Integrative Medicine, Supportive Care Unit, Chaim Sheba Medical Center, Ramat-Gan, Israel.
Objectives:
This study aims to identify and evaluate the treatment gaps in patients undergoing endocrine therapy for breast and prostate tumors, and to propose integrative solutions for unmet needs.
Methods:
The article provides a narrative review of three significant side effects of endocrine therapy among breast and prostate cancer patients: vasomotor effects, joint pain and stiffness, and sexual disorders. It also offers treatment options for these effects from the field of complementary and integrative medicine.
Results:
The adverse consequences of endocrine treatments in breast and prostate cancer patients reduce treatment compliance and significantly impair the patients' quality of life. Evidence-based complementary and integrative medicine modalities, including nutritional counseling, dietary supplements, homeopathic remedies, touch therapies, acupuncture, and mind-body treatments, may improve the patients' quality of life and alleviate the burden of side effects.
Conclusions:
There is a need to improve the management of side effects unique to endocrine therapy. Integrating supportive care with complementary and integrative medicine offers a viable option to enhance the quality of life for these patients.
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