Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Shock liver.

J S Rawson, J L Achord

    Southern Medical Journal
    |December 1, 1985
    PubMed
    Summary
    This summary is machine-generated.

    Shock liver, or ischemic hepatitis, involves rapid, severe elevations in liver enzymes due to poor blood flow, resolving within days. This condition is linked to various critical illnesses, not just low blood pressure.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Severe hepatic necrosis associated with methyldopa.

    Canadian family physician Medecin de famille canadien·2011
    Same author

    Mortality associated with spontaneous bacterial peritonitis.

    Journal of clinical gastroenterology·2001
    Same author

    American College of Cardiology/American Heart Association Clinical Competence Statement on invasive electrophysiology studies, catheter ablation, and cardioversion: A report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on Clinical Competence.

    Circulation·2000
    Same author

    American College of Cardiology/American Heart Association Clinical Competence statement on stress testing: a report of the American College of Cardiology/American Heart Association/American College of Physicians--American Society of Internal Medicine Task Force on Clinical Competence.

    Journal of the American College of Cardiology·2000
    Same author

    American College of Cardiology/American Heart Association Clinical Competence Statement on Stress Testing. A Report of the American College of Cardiology/American Heart Association/American College of Physicians-American Society of Internal Medicine Task Force on Clinical Competence.

    Circulation·2000
    Same author

    Case records of the Department of Medicine University of Mississippi Medical Center.

    Journal of the Mississippi State Medical Association·1997
    Same journal

    SMA's 6th Annual Physicians-in-Training Leadership Conference Abstract Presentations.

    Southern medical journal·2026
    Same journal

    Potential Impact of Lower Federal Loan Availability on Medical Education in Appalachia.

    Southern medical journal·2026
    Same journal

    Experiential Mentorship Skills Training: The Effect on Real-Life Mentoring.

    Southern medical journal·2026
    Same journal

    Social Pressure: How Early Social Context Shapes Career Interest in Medicine.

    Southern medical journal·2026
    Same journal

    Comparing Speed and Accuracy of Artificial Intelligence Large Language Models on the Orthopedic In-Training Examination.

    Southern medical journal·2026
    Same journal

    Don't Wait to Talk about Weight: A 2-Hour Interactive Curriculum Improves Medical Student Skills with Weight Management.

    Southern medical journal·2026
    See all related articles

    Area of Science:

    • Hepatology
    • Critical Care Medicine
    • Internal Medicine

    Background:

    • Shock liver, also known as ischemic hepatitis, presents with marked elevations in aspartate aminotransferase (AST) and alanine aminotransferase (ALT).
    • This syndrome is typically associated with cellular anoxia and decreased hepatic perfusion.
    • Previous understanding often linked it directly to systemic hypotension.

    Purpose of the Study:

    • To characterize the clinical and biochemical features of shock liver.
    • To identify underlying conditions associated with decreased cellular perfusion in patients with shock liver.
    • To evaluate the typical histologic findings in resolved cases.

    Main Methods:

    • Retrospective analysis of ten cases with clinical diagnosis of shock liver.

    Related Experiment Videos

  • Review of clinical data, including systemic blood pressure and underlying medical conditions.
  • Analysis of liver function tests (transaminases, bilirubin, alkaline phosphatase) and prothrombin time.
  • Histopathological examination of liver biopsies in two cases post-resolution.

    • Main Results:

    • Systemic hypotension was present in only 40% of cases; however, decreased cellular perfusion was identified in all.
    • Underlying causes included cardiac failure, sepsis, cerebrovascular accidents, renal failure, and COPD.
    • Transient elevations in serum bilirubin and alkaline phosphatase, and prolonged prothrombin time, followed transaminase elevations.
    • Histology did not reveal classic centrilobular necrosis in resolved cases.

    Conclusions:

    • Shock liver is characterized by a characteristic, rapidly resolving clinical and biochemical profile.
    • It is associated with a broader range of conditions causing decreased cellular perfusion, not solely systemic hypotension.
    • The distinct clinical presentation aids in differentiating it from other causes of elevated liver enzymes.