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Metastatic melanoma posing as periapical pathology: key features and learning points
Muhammed Bilaal Mirza1, Jaspreet Virdee2, Sonita Koshal3
1Dental Core Trainee in Oral Surgery and Sedation, Birmingham Dental Hospital, Birmingham, United Kingdom. b_mirza98@outlook.com.
British Dental Journal
|July 27, 2025
Summary
General dental practitioners can spot malignant melanoma, a serious cancer, in patients. Early detection and referral are crucial for managing this rising health concern.
Area of Science:
- Oncology
- Dermatology
- Oral Surgery
Background:
- Malignant melanoma is a growing health issue in the UK.
- Uncontrolled melanocyte division drives melanoma progression and high mortality.
- General dental practitioners are key in early detection and referral.
Purpose of the Study:
- To highlight the role of general dental practitioners in identifying malignant melanoma.
- To present a case of metastatic melanoma mimicking odontogenic pathology.
- To outline diagnostic clues and red flags for urgent melanoma referral.
Main Methods:
- Case report presentation.
- Review of diagnostic criteria for oral melanoma.
- Discussion of referral pathways for suspicious lesions.
Main Results:
- A case of metastatic malignant melanoma presented as odontogenic pathology.
- Timely referral to Oral Surgery was critical for management.
- Specific diagnostic clues were identified.
Conclusions:
- Malignant melanoma can present atypically in the oral cavity.
- Dental practitioners are vital in recognizing and referring potential melanoma cases.
- Prompt identification and management improve patient outcomes.

