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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT

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Radiologic Follow-up of Vascular Structures in Gastric Cancer Patients Receiving Adjuvant Radiotherapy.

F Karaca¹, S Keskin², H Akkaya³

¹Department of Radiation Oncology, Adana City Training and Research Hospital, Adana, Turkey.

Nigerian Journal of Clinical Practice

|July 27, 2025

Summary

Radiotherapy (RT) for gastric cancer patients led to a reduction in the diameters of the portal vein (PV) and celiac artery (CA). These vascular structure changes were observed three months post-treatment.

Keywords:

Gastric cancer radiological radiotherapy

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Area of Science:

Medical Imaging
Oncology
Radiology

Background:

Gastric cancer patients often receive adjuvant radiotherapy (RT) and chemotherapy.
Vascular structure changes following RT are a significant concern.

Purpose of the Study:

To investigate the impact of adjuvant RT on vascular structures in gastric cancer patients.
To quantify changes in portal vein (PV) and celiac artery (CA) diameters post-RT.

Main Methods:

Computed tomography (CT) scans were used to measure PV and CA diameters.
Measurements were taken before RT (RT0) and 3 months after RT (RT1) in 33 patients.
Adjuvant external RT was administered at curative doses.

Main Results:

A statistically significant decrease of 0.31 mm in PV diameter was observed from RT0 to RT1 (P < 0.05).
A decrease of 0.24 mm in CA diameter was also noted when comparing RT0 and RT1 measurements.

Conclusions:

Adjuvant RT in gastric cancer patients resulted in smaller diameters of the celiac artery and portal vein.
These findings highlight potential vascular alterations following RT for gastric cancer.