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Related Concept Videos

Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
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Clinical Outcomes and Prognostic Factors of Percutaneous Transhepatic Biliary Drainage in Malignant Biliary Obstruction: A Retrospective Study of 383 Patients.

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Related Experiment Video

Updated: Apr 1, 2026

An Orthotopic Endometrial Cancer Model with Retroperitoneal Lymphadenopathy Made From In Vivo Propagated and Cultured VX2 Cells
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Radiology of Endometrial Cancer Receiving Adjuvant Radiotherapy.

F Karaca1, S Keskin2, S Menteş1

  • 1Department of Radiation Oncology, Adana City Training and Research Hospital, Adana, Türkiye.

Nigerian Journal of Clinical Practice
|March 30, 2026
PubMed
Summary
This summary is machine-generated.

External beam radiotherapy (EBRT) for endometrial cancer (EC) caused significant decreases in rectal diameter and some pelvic blood vessels within three months. These early changes suggest potential radiation tissue damage requiring further monitoring.

Keywords:
Adjuvantendometrial neoplasmsfemoral arteryiliac arterymagnetic resonance ımagingradiotherapyrectum

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Area of Science:

  • Oncology
  • Radiotherapy
  • Medical Imaging

Background:

  • Endometrial cancer (EC) treatment often involves surgery followed by radiotherapy (RT).
  • Limited research exists on the early effects of RT on pelvic blood vessels and rectal tissues post-treatment.
  • Understanding these changes is crucial for managing potential side effects.

Purpose of the Study:

  • To investigate the impact of external beam radiotherapy (EBRT) on pelvic blood vessel and rectal tissue dimensions in EC patients.
  • To assess early changes using contrast-enhanced magnetic resonance imaging (CE-MRI) during the initial post-treatment period.

Main Methods:

  • Ninety-five female EC patients undergoing adjuvant EBRT were included.
  • CE-MRI scans were performed before RT (RT0) and 3 months after (RT1).
  • Measurements included rectum and iliac/femoral artery diameters.

Main Results:

  • Significant decreases were observed in rectum external diameter (RED), right femoral artery diameter (RFAD), left femoral artery diameter (LFAD), and left external iliac artery diameter (LEIAD) at RT1 compared to RT0 (P < 0.05).
  • No significant changes were found in rectum internal diameter (RID) or right external iliac artery diameter (REIAD).
  • These findings indicate differential early tissue responses to EBRT.

Conclusions:

  • EBRT treatment led to measurable reductions in rectal wall and specific pelvic blood vessel diameters within 3 months.
  • These early changes detected by CE-MRI may indicate initial radiation tissue damage.
  • Further evaluation with extended patient monitoring is recommended to understand the long-term implications.