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Feline Conjunctival Sequestra-A Case Series
Carolina Cauduro da Rosa1, Brett D Story2, Sangwan Park2
1Comparative Ophthalmology Laboratory, Federal University of Paraná, UFPR, Curitiba, Brazil.
Veterinary Ophthalmology
|July 28, 2025
Summary
This study describes feline conjunctival sequestra, a novel condition in cats. Histopathology revealed collagen compaction, similar to corneal sequestra, with possible links to chronic irritation or FHV-1 infection.
Area of Science:
- Veterinary Ophthalmology
- Feline Pathology
Background:
- Corneal sequestrum is a known feline eye condition with unclear causes.
- Conjunctival sequestrum has not been previously documented in cats.
Purpose of the Study:
- To report the first series of cases of conjunctival sequestrum in cats.
- To describe the clinical and histopathological features of this condition.
Main Methods:
- A retrospective search of the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW) database identified five cases.
- Ophthalmological examination revealed black plaques in the conjunctiva.
- Histopathology was performed on conjunctival and concurrent corneal lesions.
Main Results:
- Conjunctival lesions showed focally extensive compaction and brunescence of proprial collagen without fibroblasts.
- Three cases had overlying conjunctival ulceration.
- The appearance was similar to feline corneal sequestra, with variable inflammation and microorganisms.
Conclusions:
- This is the first case series documenting feline conjunctival sequestrum.
- Concurrent ocular abnormalities were variable, preventing a definitive cause.
- Chronic irritation and potential Feline Herpesvirus-1 (FHV-1) infection are suspected etiologies.
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