Mandibular Reconstruction Using Freeze-Dried Cortical and Cancellous Allografts and Titanium Locking Miniplates in 3...

This case series describes the use of cortical allografts, cancellous allografts with and without recombinant human platelet-derived growth factor-BB, and titanium locking plates for repair of critical-sized defects in 4 mandibles from 3 canine patients. Two mandibles were repaired after oncologic surgery and 2 mandibles were reconstructed due to chronic nonunion fractures. Various techniques were utilized for maintenance of the occlusion intraoperatively. All patients that received postoperative imaging showed evidence of integration of the allograft with the host bone, demonstrating the validity of this technique as a method of repair for mandibular critical-sized defects in dogs.