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Granulomatosis With Polyangiitis (GPA): A Case Report
Rana Hoseen1,2, Sara G Haroutunian3,2,4, Salvatore Grasso3,2
1Internal Medicine, Ross University School of Medicine, Miramar, USA.
Abstract:
Granulomatosis with polyangiitis (GPA) is a rare necrotizing vasculitis disease affecting small to medium vessels. The exact cause of GPA is not fully understood, but the inflammation is associated with anti-neutrophil-cytoplasmic-antibody (ANCA). GPA involves the upper and lower respiratory tract, systemic vasculitis, and glomerulonephritis. This case report describes a young female patient presenting with a dry cough for a month that did not improve with Bactrim, weight loss, sinusitis, mastoid effusion, and multiple mass-like infiltrates in the lungs on imaging, who was found to have GPA vasculitis after being confirmed with a biopsy.
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