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Updated: Sep 13, 2025

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Single-layer vs Double-layer Intestinal Anastomosis: A Prospective Comparative Study.

Shahbaz Bashir1, Naiem Ahrar2, Mudassir S Khurshid2

  • 1Department of General and Minimal Access Surgery, Sher-i-Kashmir Institute of Medical Sciences (SKIMS) Soura, Srinagar, Jammu and Kashmir, India.

Euroasian Journal of Hepato-Gastroenterology
|July 28, 2025
PubMed
Summary
This summary is machine-generated.

Single-layer intestinal anastomosis is quicker to perform than double-layer, with no significant differences in leak rates or hospital stay. Low preoperative albumin levels are linked to increased anastomotic leak risk.

Keywords:
Anastomotic leakDouble-layerIntestinal anastomosisOperative timeSingle-layer

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Area of Science:

  • Gastroenterology
  • Surgical Techniques
  • Clinical Research

Background:

  • Intestinal anastomosis is a critical surgical procedure.
  • The choice between single-layer and double-layer techniques can impact patient outcomes.
  • Understanding the comparative efficacy of these methods is essential for surgical practice.

Purpose of the Study:

  • To compare single-layer versus double-layer intestinal anastomosis.
  • To evaluate differences in anastomotic leak rates, hospital stay duration, and surgical time.
  • To investigate the relationship between preoperative albumin (Alb) and hemoglobin (Hb) levels and anastomotic leak risk.

Main Methods:

  • A prospective comparative study involving 20-75 year old patients undergoing intestinal anastomosis.
  • Patients were divided into two groups: single-layer anastomosis (Group A) and double-layer anastomosis (Group B).
  • Data collected included operative time, postoperative complications (anastomotic leak), and length of hospital stay.

Main Results:

  • Single-layer anastomosis took significantly less time (17.68 min) compared to double-layer (27.22 min).
  • Anastomotic leak rates were similar: 6.8% in single-layer and 9.1% in double-layer.
  • Mean hospital stay was comparable: 6.6 days (single-layer) vs. 7.21 days (double-layer).

Conclusions:

  • Single-layer intestinal anastomosis is faster to perform than double-layer.
  • There is no significant difference in anastomotic leak rates or hospital stay duration between the two techniques.
  • Low preoperative albumin levels are associated with an increased risk of anastomotic leak.