Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Operon Model01:23

Operon Model

118
The operon model represents a fundamental mechanism of gene regulation in prokaryotes, enabling coordinated expression of genes involved in related metabolic or functional pathways. Operons consist of structural genes, a promoter, and an operator, with transcription regulated by repressors, activators, and small effector molecules.Structure and Function of OperonsAn operon is a cluster of structural genes transcribed together under the control of a single promoter. The promoter region...
118

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Therapeutic Potential of Phellodendrine/ Atractylenolide-I Combination in Rheumatoid Arthritis: Targeting Neutrophil Apoptosis Through LTB4/BLT1 Pathway Suppression.

Endocrine, metabolic & immune disorders drug targets·2026
Same author

Erector spinae plane block for opioid sparing in children undergoing laparoscopic appendectomy: a randomized controlled trial.

Frontiers in pediatrics·2026
Same author

Acute susceptibility changes of deep gray matter nuclei to gadobutrol: a prospective longitudinal study using quantitative susceptibility mapping.

Quantitative imaging in medicine and surgery·2026
Same author

LncRNA HOXA11-AS promotes idiopathic pulmonary fibrosis progression via sponging miR-148a-3p and regulating SMAD2.

Hereditas·2026
Same author

Di-2-ethylhexyl Phthalate Reprograms Epithelial-Mesenchymal Transition and Lenvatinib Responsiveness in Hepatoma Cells via SPAG4-Dependent MAPK/ERK Signaling.

Chemical research in toxicology·2026
Same author

Unlocking Photocatalytic CO<sub>2</sub> Conversion to Ethylene Glycol by Microdroplet-Enabled Interfacial Electric Field.

Angewandte Chemie (International ed. in English)·2026
Same journal

Correction: Komatsu et al. Three-Dimensional Visualization and Detection of the Pulmonary Venous-Left Atrium Connection Using Artificial Intelligence in Fetal Cardiac Ultrasound Screening. <i>Bioengineering</i> 2026, <i>13</i>, 100.

Bioengineering (Basel, Switzerland)·2026
Same journal

Comparison of CO<sub>2</sub> Laser and Microdebrider in the Surgical Treatment of Pediatric Recurrent Respiratory Papillomatosis: A Retrospective Analysis.

Bioengineering (Basel, Switzerland)·2026
Same journal

Toward More Translational Tumor Models: Breast dECM-Based 3D Systems Capture Native Microenvironmental Cues.

Bioengineering (Basel, Switzerland)·2026
Same journal

Postural Stability Changes During the 4 Phases of the Half Squat: Kinematics Profile of the Center of Pressure and Center of Mass in High-Performance Weightlifters-A Pilot Study.

Bioengineering (Basel, Switzerland)·2026
Same journal

Definite Implant Position as Novel Readout for Effectiveness of Ridge Preservation Indicates to Beneficial Effect of Combined Treatment with Platelet-Rich Fibrin (PRF) and Xenogenic Biomaterial in Bone Regeneration.

Bioengineering (Basel, Switzerland)·2026
Same journal

Trueness and Precision of Intraoral Scanners for 3D-Printed Orthodontic Models with Attachments: An In Vitro Comparative Study.

Bioengineering (Basel, Switzerland)·2026
See all related articles

Related Experiment Video

Updated: Sep 13, 2025

Creating Rapid Oxygen Oscillations in Microbial Single-cell Growth Analysis using a Microfluidic Double-layer Device
08:28

Creating Rapid Oxygen Oscillations in Microbial Single-cell Growth Analysis using a Microfluidic Double-layer Device

Published on: July 18, 2025

116

Modeling and Dynamic Parameterized Predictive Control of Dissolved Oxygen in Dual-Tank Bioreactor Systems.

Muhang Li1,2, Ran Tang1,2, Yifei Li3

  • 1Center of Ultra-Precision Optoelectronic Instrument Engineering, Harbin Institute of Technology, Harbin 150080, China.

Bioengineering (Basel, Switzerland)
|July 29, 2025
PubMed
Summary
This summary is machine-generated.

A new dynamic parameterized predictive control (DPPC) method improves dissolved oxygen (DO) distribution in bioreactors. This advanced control strategy ensures faster, more stable oxygen supply for sensitive culture systems.

Keywords:
bioreactor optimizationdissolved oxygendynamic parameterized predictive controloxygen distributionrecirculating culture

More Related Videos

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities
08:13

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities

Published on: December 25, 2015

17.2K
Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation
08:17

Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation

Published on: August 14, 2020

5.3K

Related Experiment Videos

Last Updated: Sep 13, 2025

Creating Rapid Oxygen Oscillations in Microbial Single-cell Growth Analysis using a Microfluidic Double-layer Device
08:28

Creating Rapid Oxygen Oscillations in Microbial Single-cell Growth Analysis using a Microfluidic Double-layer Device

Published on: July 18, 2025

116
A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities
08:13

A Novel Bioreactor for High Density Cultivation of Diverse Microbial Communities

Published on: December 25, 2015

17.2K
Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation
08:17

Coupling Carbon Capture from a Power Plant with Semi-automated Open Raceway Ponds for Microalgae Cultivation

Published on: August 14, 2020

5.3K

Area of Science:

  • Biotechnology
  • Chemical Engineering
  • Control Systems

Background:

  • Dissolved oxygen (DO) distribution and system response are critical in dual-tank recirculating bioreactors.
  • Uneven DO levels and delayed responses present significant challenges for optimal culture conditions.

Purpose of the Study:

  • To develop and validate a novel control approach for enhanced DO management in bioreactors.
  • To address limitations of conventional feedback control in dynamic recirculating systems.

Main Methods:

  • A dynamic parameterized predictive control (DPPC) strategy was developed.
  • The DPPC is based on a mathematical model integrating mass transfer kinetics and chemical thermodynamics.
  • The approach was validated using simulations and bench-scale experiments in dual-tank bioreactors.

Main Results:

  • The DPPC method accurately predicts future DO variations by integrating real-time data.
  • Experimental results showed high predictive accuracy (RMSE < 0.05, R² > 0.99).
  • DPPC demonstrated superior performance over conventional methods, with significant reductions in integrated square error (ISE) and integrated absolute error (IAE).

Conclusions:

  • The DPPC approach offers improved stability, faster response times, and reduced overshoot in DO control.
  • This method shows significant promise for controlling oxygen-sensitive culture systems.
  • DPPC provides a robust framework for real-time oxygen supply optimization in bioreactors.