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Aortic Regurgitation III: Medical Management

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...

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Related Experiment Video

Updated: Sep 13, 2025

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

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Innovations in TAVR: The Latest in Device Technology.

Omar Sheikh¹, Errol Moras², Lorraine Mascarenhas¹

¹Section of Cardiology, Baylor College of Medicine, Houston, TX 77030, USA.

Journal of Clinical Medicine

|July 29, 2025

Summary

This summary is machine-generated.

Transcatheter aortic valve replacement (TAVR) is a leading treatment for aortic stenosis, now benefiting younger patients and complex anatomies. Innovations enhance TAVR safety and efficacy, though challenges persist.

Keywords:

TAVR THV design leaflet modification

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Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Upper-extremity Approach for Secondary Access in Transfemoral Transcatheter Aortic Valve Implantation

Published on: August 8, 2025

Area of Science:

Cardiology
Interventional Cardiology
Biomedical Engineering

Background:

Aortic stenosis is the most common global valvular heart disease.
Transcatheter aortic valve replacement (TAVR) offers outcomes comparable to surgical aortic valve replacement (SAVR).
TAVR is increasingly used in younger, lower-risk patients and those with complex anatomies.

Purpose of the Study:

To review recent advancements in transcatheter heart valve (THV) systems.
To highlight innovations in TAVR technology and devices.
To discuss current limitations and challenges in TAVR procedures.

Main Methods:

Review of recent literature on TAVR advancements.
Analysis of new transcatheter heart valve (THV) systems.
Examination of leaflet modification devices and TAVR limitations.

Main Results:

Transfemoral access is more common.
Prosthesis designs are optimized for challenging anatomies.
Enhanced delivery systems offer repositioning, and outer skirts reduce paravalvular leaks.

Conclusions:

TAVR technology continues to evolve rapidly.
Innovations are expanding TAVR applicability and improving patient outcomes.
Addressing remaining challenges is crucial for further TAVR adoption and success.