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Updated: Sep 8, 2025

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Transcanalicular Diode Laser-assisted Dacryocystorhinostomy for the Treatment of Primary Acquired Nasolacrimal Duct Obstruction
Published on: October 13, 2017
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Pigmented, Birefringent Material Causing Nasolacrimal Duct Obstruction
Angela L Xu1, César A Briceño2, Vivian Lee2
1Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.
Summary
Epiphora (watery eye) can result from nasolacrimal duct obstruction caused by cosmetic particles. Histopathology is crucial to distinguish cosmetic-induced inflammation from melanoma.
Area of Science:
- Ophthalmology
- Pathology
Background:
- Epiphora, or watery eye, is a common condition.
- Nasolacrimal duct obstruction (NLDO) is a frequent cause of epiphora.
- Distinguishing between innate melanocytic processes and exogenous causes of NLDO is clinically important.
Purpose of the Study:
- To present a case of epiphora caused by cosmetic-induced foreign bodies in the nasolacrimal duct.
- To highlight the importance of histopathological examination in diagnosing the cause of NLDO.
Main Methods:
- Case report of a woman presenting with epiphora.
- Histopathological analysis of tissue from the nasolacrimal duct.
- Identification of pigmented, birefringent foreign bodies consistent with cosmetics.
Main Results:
- Complete nasolacrimal duct obstruction was diagnosed.
- Granulomatous inflammation was observed around foreign bodies.
- Foreign bodies were identified as consistent with cosmetic particles.
Conclusions:
- Cosmetic particles can cause granulomatous inflammation leading to nasolacrimal duct obstruction and epiphora.
- Patient history and histopathology are essential for accurate diagnosis, differentiating cosmetic-induced issues from conditions like melanoma.
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