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The Journey of Functional Nanoparticles in the Human Hard Tissue Mineralization: Classification, Key Functions, and
Tianjia Huang1, Shuwei Qiao1, Jiawen Wang1
1Department of Prosthetic Dentistry, School and Hospital of Stomatology, Jilin University, Changchun, 130021, P. R. China.
Small (Weinheim an Der Bergstrasse, Germany)
|July 29, 2025
Summary
Nanoparticles (NPs) offer innovative solutions for human hard tissue mineralization, aiding bone and tooth repair. This review explores NP applications in biomimetic mineralization and nanomedicine for enhanced tissue regeneration.
Area of Science:
- Biomaterials Science
- Nanotechnology
- Biomineralization
Background:
- Human hard tissue mineralization is crucial for self-renewal and repair.
- Nanoparticles (NPs) offer unique properties like high surface area and tunable functions.
- NPs present novel therapeutic strategies for bone and tooth defects.
Purpose of the Study:
- To review the process of human hard tissue mineralization from physicochemical and biomineralization viewpoints.
- To classify and detail the NPs used in hard tissue mineralization.
- To discuss the functions and potential of NPs in promoting mineralization.
Main Methods:
- Literature review of physicochemical and biomineralization processes.
- Classification and analysis of nanoparticles used in hard tissue mineralization.
- Examination of NP synthesis, structure, and modifications.
Main Results:
- Human hard tissue mineralization involves complex physicochemical and biological processes.
- Various nanoparticles are utilized, with diverse synthesis methods and structures.
- Multifunctional modifications enhance NP capabilities for mineralization.
- NPs show potential as carriers for mineralization-promoting agents.
Conclusions:
- Nanoparticles are promising tools for enhancing human hard tissue mineralization.
- Further research into biomimetic mineralization and nanomedicine is warranted.
- NPs can be engineered as effective delivery systems for therapeutic ions, drugs, and molecules.
Keywords:
biomimetic mineralizationcollagenhuman hard tissue mineralizationmineralizationnanoparticlesMore Related Videos
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