Related Experiment Video
Updated: Sep 13, 2025

A Robust Discovery Platform for the Identification of Novel Mediators of Melanoma Metastasis
Published on: March 8, 2022
[Noninvasive imaging of cutaneous melanoma metastases : Microenvironment and vascular insights in therapy]
Oliver Mayer1, Rebecca Schönherr2, Julia Welzel2
1Klinik für Dermatologie und Allergologie, Universitätsklinikum Augsburg, Sauerbruchstr. 6, 86179, Augsburg, Deutschland. oliver.mayer@uk-augsburg.de.
Abstract:
A 63-year-old man with cutaneous melanoma metastases showed a strong therapeutic response to combined immunotherapy with ipilimumab and nivolumab. Using dynamic optical coherence tomography (D-OCT) and line-field confocal optical coherence tomography (LC-OCT), a significant reduction in vessel density and diameter was noninvasively observed. These vascular changes reflect the tumor microenvironment's response to therapy and highlight the potential of noninvasive imaging in treatment monitoring.

