Infantile Hemangioma: Risk Factors and Management in a Preterm Patient-A Case Report

Florica Sandru1,2, Aida Petca3,4, Andreea-Maria Radu2

  • 1Department of Dermatovenerology, University of Medicine and Pharmacy "Carol Davila", 020021 Bucharest, Romania.

Reports (MDPI)
|July 29, 2025
PubMed

Insights

Infantile hemangiomas (IHs) are common benign tumors in infants. This case report details successful propranolol and topical treatment for IHs in a preterm infant, highlighting risk factors and management.

Area of Science:

  • Pediatric Oncology
  • Dermatology
  • Neonatology

Background:

  • Infantile hemangiomas (IHs) are the most common benign tumors in infants, affecting 4-10% of newborns.
  • Risk factors for IHs include preterm birth and low birth weight.
  • Maternal factors like anemia and cervical cerclage may also be associated with IH development.

Observation:

  • A case of a preterm infant (27 weeks gestation, 1010g birth weight) with multiple IHs is presented.
  • IHs appeared on the frontal hairline and right arm within the first month of life.
  • The infant's mother experienced anemia and required cervical cerclage during pregnancy.

Findings:

  • The infant received propranolol oral suspension for 10 months, followed by 2 months of local ointment treatment.
  • This combined therapeutic approach yielded excellent results.
  • No adverse reactions were reported during the treatment course.

Implications:

  • This case underscores the importance of recognizing IHs in preterm infants.
  • It highlights the efficacy and safety of propranolol and topical treatments for infantile hemangiomas.
  • Understanding risk factors and treatment options is crucial for managing IHs.

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