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Cyber-Physical System Interface for Implantable Esophageal Prosthesis.

Ana Magdalena Anghel¹, Teodora Mîndra¹

¹Faculty of Automatic Control and Computers, National University of Science and Technology POLITEHNICA Bucharest, 313 Splaiul Independenței, 060042 Bucharest, Romania.

Sensors (Basel, Switzerland)

|July 30, 2025

Summary

This study introduces a Cyber-Physical System Interface (CPSI) for implantable esophageal prostheses, enabling real-time monitoring of device position and interactions. The CPSI framework facilitates analysis of prosthesis geometry and tissue response for improved in vivo implant development.

Keywords:

Cyber-Physical System Interface esophageal prosthesis implants

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Area of Science:

Biomedical Engineering
Medical Device Technology
Cyber-Physical Systems

Background:

Implantable medical devices require robust monitoring systems for in vivo performance evaluation.
Esophageal prostheses present unique challenges for tracking position and assessing tissue interaction.
Existing monitoring methods may lack the integration and real-time capabilities needed for complex implants.

Purpose of the Study:

To develop and implement a Cyber-Physical System Interface (CPSI) for an implantable esophageal prosthesis.
To create a simulation environment for analyzing the prosthesis's physical positioning and environmental interactions.
To demonstrate the CPSI's utility in evaluating prosthesis geometry variations and tissue response.

Main Methods:

Implementation of a Cyber-Physical System Interface (CPSI) in MATLAB (R2021b).
Integration of real-time sensor data aggregated via an Arduino external system.
Development of a simulation framework for in vivo implant monitoring and analysis.

Main Results:

Successful implementation of a CPSI for an implantable esophageal prosthesis in a simulation environment.
Demonstration of two case studies: prosthesis geometry variation analysis and tissue response evaluation.
Validation of the sensor-to-display flow for real-time monitoring.

Conclusions:

The proposed CPSI provides a versatile framework for monitoring in vivo implants.
The system enables detailed analysis of implant performance and biological interactions.
This approach is highly relevant for the development and refinement of various implantable medical devices.