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Updated: Sep 13, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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The Role of Trifluoromethyl and Trifluoromethoxy Groups in Medicinal Chemistry: Implications for Drug Design

Manuel Novás1, Maria J Matos1

  • 1Departamento de Química Orgánica, Facultad de Farmacia, Universidade de Santiago de Compostela, 15782 Santiago de Compostela, Spain.

Molecules (Basel, Switzerland)
|July 30, 2025
PubMed

Keywords:
drug designmedicinal chemistrytrifluoromethoxy grouptrifluoromethyl group

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