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Updated: Sep 13, 2025

A Method for Selecting Structure-switching Aptamers Applied to a Colorimetric Gold Nanoparticle Assay
Published on: February 28, 2015
Colorimetric ALP detection with a ligand-exchanged Au8 cluster
Jingjing Yang1, Qing You2, Qian Wang1
1Institutes of Physical Science and Information Technology, Key Laboratory of Structure and Functional Regulation of Hybrid Materials of Ministry of Education, Anhui University, Hefei, 230601, China. 20231@ahu.edu.cn.
Abstract:
An atomically precise Au8 nanocluster (dppm/dppp) synthesized via ligand exchange exhibits oxidase-like activity. Alkaline phosphatase (ALP) quenches O2˙-, enabling sensitive and specific colorimetric detection and demonstrating diagnostic potential.
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