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Related Experiment Video

Updated: Sep 13, 2025

Dual-Task Stroop Paradigm for Detecting Cognitive Deficits in High-Functioning Stroke Patients
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Elderly stroke burden: a comprehensive global study over three decades.

Ruoyu Gou1, Changjun Luo2, Xudong Liang2

  • 1School of Public Health, Ningxia Medical University, Yinchuan, Ningxia, China.

Frontiers in Aging
|July 30, 2025
PubMed
Summary

Stroke cases and deaths in the elderly increased globally from 1990-2021. Despite rising numbers, age-standardized incidence and mortality rates decreased, with older men experiencing a higher burden.

Keywords:
GBDdisability-adjusted life-yearselderly patientincidencemortalitystroke

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Area of Science:

  • Gerontology
  • Epidemiology
  • Public Health

Background:

  • Stroke represents a significant global health challenge, impacting elderly patients' quality of life.
  • The Global Burden of Disease (GBD) study provides critical data for understanding disease prevalence and impact.

Purpose of the Study:

  • To analyze the trends in stroke burden among the elderly population worldwide from 1990 to 2021.
  • To assess changes in stroke incidence, mortality, and disability-adjusted life years (DALYs) in older adults.

Main Methods:

  • Utilized cross-sectional data from the Global Burden of Disease (GBD) 2021 study.
  • Analyzed morbidity, mortality (all-cause and cause-specific), and DALYs for stroke in the elderly across 204 countries and territories.
  • Calculated estimated annual percentage changes (EAPCs) to determine trend rates.

Main Results:

  • Global stroke cases in the elderly increased from 4.39 to 8.19 million (1990-2021).
  • Age-standardized incidence (ASIR) and mortality rates (ASMR) decreased significantly, with EAPCs of -0.784 and -1.446, respectively.
  • Disability-adjusted life years (DALYs) increased, while the age-standardized DALYs rate (ASDR) declined. Stroke burden was higher in men than women across five Socio-Demographic Index (SDI) regions.

Conclusions:

  • The overall number of stroke cases, deaths, and DALYs has risen in the elderly population.
  • Despite increasing case counts, global age-standardized stroke incidence and mortality rates have declined.
  • Older men face a disproportionately higher burden of stroke compared to older women.