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Material properties and progress in modification of hydrogel-based self-expandable poly(methyl methacrylate) bone
Haochang He1, Yuanbiao Liu1, Yukai Dong1
1School of Materials Science & Engineering, Shandong University of Technology Zibo 255000 China zhanghj@sdut.edu.cn.
RSC Advances
|July 30, 2025
Summary
Self-expandable bone cement (SBC) offers improved bioactivity and adjustable mechanical properties compared to traditional poly(methyl methacrylate) (PMMA) bone cements. SBC shows promise as a superior alternative for bone tissue repair and orthopedic applications.
Area of Science:
- Biomaterials Science
- Orthopedic Surgery
- Polymer Chemistry
Background:
- Traditional poly(methyl methacrylate) (PMMA) bone cements have limitations including high polymerization heat, poor bioactivity, and volumetric shrinkage.
- These drawbacks restrict the clinical application of PMMA bone cements in bone tissue repair.
Purpose of the Study:
- To review the material properties and modifications of self-expandable bone cement (SBC).
- To discuss the influence of functional monomers and fillers on SBC's biomechanical properties.
- To propose future research directions for SBC development.
Main Methods:
- Review of existing literature on self-expandable bone cement (SBC).
- Analysis of the impact of hydrophilic monomers on SBC properties.
- Evaluation of filler and antibiotic incorporation in SBC formulations.
Main Results:
- Self-expandable bone cement (SBC) exhibits enhanced bioactivity and tunable mechanical properties.
- SBC demonstrates excellent volumetric swelling due to water absorption in body fluids.
- SBC can incorporate antibiotics and fillers to prevent infection and achieve desired biomechanical performance.
Conclusions:
- Self-expandable bone cement (SBC) is a promising alternative to conventional PMMA bone cements.
- SBC's adjustable properties and bioactivity make it suitable for various orthopedic applications.
- Further research into SBC modifications can optimize its clinical utility.
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