Related Experiment Video
Updated: Sep 13, 2025
08:50
A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
Published on: June 24, 2020
3.9K
Candida glabrata chorioamnionitis following IVF pregnancy
Junais Koleri1, Hani Ghassan Hamad1, Fatma Ben Abid1
1Department of Infectious Diseases, Communicable Diseases Centre, Hamad Medical Corporation, Qatar.
Idcases
|July 30, 2025
Summary
A rare fungal infection, Candida glabrata chorioamnionitis, occurred in a twin pregnancy conceived via in vitro fertilization (IVF). Early diagnosis and antifungal treatment were crucial for maternal survival.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Reproductive Medicine
Background:
- Fungal chorioamnionitis is a rare pregnancy complication.
- Candida glabrata is an opportunistic fungal pathogen.
- Assisted reproductive technologies, like IVF, may increase infection risk.
Observation:
- A severe case of Candida glabrata chorioamnionitis occurred in a 19-week twin pregnancy conceived via IVF.
- The patient experienced maternal septic shock and fetal demise.
- Candida glabrata was identified in blood and placental cultures.
Findings:
- The patient was successfully treated with anidulafungin.
- Early identification of C. glabrata was key to treatment.
- The case underscores the link between IVF and fungal chorioamnionitis.
Implications:
- Increased awareness of fungal chorioamnionitis in IVF pregnancies is needed.
- Early diagnosis and prompt management are critical.
- Consideration for pre-procedural screening and prophylaxis in high-risk IVF patients may be warranted.
Related Concept Videos
01:24In Vitro Fertilization
395
In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
395
01:28Infertility in Females
404
Female infertility is defined as the inability to conceive after a year of regular, unprotected intercourse and affects about 10–15% of couples worldwide. The primary cause of female infertility is ovulatory disorders, which hinder the release of eggs. These disorders can be classified as hypothalamic amenorrhea, polycystic ovarian syndrome (PCOS), premature ovarian failure, and hyperprolactinemic anovulation disorders.
Endometriosis, a condition characterized by abnormal growth of...
Endometriosis, a condition characterized by abnormal growth of...
404
01:26Sexually Transmitted Infections
415
Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
415
01:15Transcytosis of IgG
2.9K
Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
2.9K
01:17Urinary Tract Infection IV: Nursing Management
88
In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs...
88
01:38Fertilization
72.3K
During fertilization, an egg and sperm cell fuse to create a new diploid structure. In humans, the process occurs once the egg has been released from the ovary, and travels into the fallopian tubes. The process requires several key steps: 1) sperm present in the genital tract must locate the egg; 2) once there, sperm need to release enzymes to help them burrow through the protective zona pellucida of the egg; and 3) the membranes of a single sperm cell and egg must fuse, with the sperm...
72.3K