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X-Linked Juvenile Retinoschisis
Leticia Pinheiro1, Stephen H Tsang2, Tarun Sharma3
1Federal University of Goiás, Goiânia, Brazil.
Advances in Experimental Medicine and Biology
|July 30, 2025
Abstract:
X-linked juvenile retinoschisis (XLRS) occurs exclusively in males and is characterized by visual loss that begins in early childhood; patients are usually school-age and are experiencing visual disturbances, especially in reading. The prevalence is estimated to be 1 in 5000-25,000 men, worldwide. XLRS has complete penetrance but variable expressivity. Carrier females generally remain asymptomatic.
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